WS C621E SAGE
The Intel® C621 motherboard supports quad-intensity graphics and 12 DDR4 memory slots, while executing multiple RAM-intensive applications such as video, audio, and video editing applications is not a problem.

Application Field

Simultaneous execution of multiple RAM-intensive applications (such as video, audio, and video editing applications) is not a problem

Product Features

Intel® C621 motherboard supports quad-intensity graphics and 12 DDR4 memory slots


  • 4-way NVIDIA® SLI® and AMD® Crossfire XTM, on-demand

  • Dual Xeon® CPU OC adjustment for outstanding performance

  • Built-in U.2, M.2, USB 3.1 Type-C and Type-A for superior scalability and connectivity

  • High quality components for higher power efficiency

  • Easily manage and maintain with ASUS Remote Control Center (ACC) management software and USB BIOS FlashbackTM


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4-way multi-graphics card


The Intel® C621 chipset dual-socket workstation motherboard features on-demand NVIDIA® SLITM and AMD® CrossFireXTM technology.

The ASUS WS C621E SAGE features four PCIe Gen3 x16 links for four dual-width graphics for higher graphics performance.

Supports 4-way NVIDIA® SLITM, AMD CrossFireXTM, 2-way NVIDIA Quadro® SLITM WS C621E SAGE

Ideal for content creators, mechanical or construction engineers, and anyone dealing with intensive workloads.



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Dual Intel® Xeon® CPU overclocking provides greater performance


Dual Intel® Xeon® CPU overclocking for greater processing power

ASUS WS C621E SAGE breaks performance limits and provides dual Xeon® CPU overclocking.

With a BIOS mechanism that specifically improves CPU performance, the WS C621E SAGE provides faster system speeds.


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Supports 12 DDR4 Error Correction Code Memory (ECC Memory)


Even with multiple hardware-intensive programs, the system runs fast! ASUS WS C621E SAGE is supported

12 DDR4 Error Correction Code (ECC) memories for fast, sensitive system performance, even when executed simultaneously

RAM-intensive applications such as video, audio, and video editing applications are also not a problem.


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Support NVMe PCIe SSD RAID 0, storage speed


ASUS WS C621E SAGE supports configuring multiple NVMe PCIe storage devices as RAID 0 arrays.

Let you enjoy fast data transfer beyond a single disk drive.


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Built-in four U.2 and M.2 for fast speeds up to 32Gbps


The ASUS WS C621E SAGE has built-in M.2 and U.2 interfaces for 2.5-inch NVMe and M.2 SSD.

The WS C621E SAGE uses PCIe Gen3.0 x4 bandwidth 32Gbps to achieve approximately 5.3 times faster data transfer speed than traditional storage devices.


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Built-in 10Gb/s USB 3.1 Gen2


Equipped with backward compatible USB 3.1 Gen2 Type-A and USB 3.1 Gen2 Type-C front and back connectors.

Lets you enjoy connection flexibility and data transfer speeds of up to 10Gb/s — theoretically about twice as fast as USB 3.0 or USB 3.1 Gen1.


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Realtek® codec sound features and special design

Deliver pure, powerful sound



Not satisfied with the read/write speed of a single storage device? Then speed up and build RAID 0 arrays with NVMe PCIe storage drives for faster data transfer!





Technical Specifications

Product Model WS C621E SAGE
CPU Dual Intel® Socket P (LGA 3647) for Intel® Xeon® Scalable Processors Family (205W)
Motherboard Chipset 支持英特尔® C621
USB ASMedia® USB 3.1 Gen 2 控制器 :
2 x USB 连接端口 (2 @后, , Type-A + USB Type-C)
英特尔® C621 芯片组 :
8 x USB 3.1 Gen 1 连接端口 (4 @后, , 4 @前)
英特尔® C621 芯片组 :
4 x USB 2.0 连接端口 (2 @后, , 2 @前)
RAM 12 x DIMM, 容量可达 768GB, DDR4 2666/2400 MHz RDIMM, LR-DIMM 内存
Network Card Intel® I210-AT, 2 x 千兆网卡
Internet Intel® I210-AT, 2 x 千兆网卡
Storage Function 英特尔® C621 芯片 :
8 x SATA 6Gb/s 接口 ,
支持 Raid 0, 1, 5, 10
ASMedia® SATA 6Gb/s 控制器 :
2 x SATA 6Gb/s 接口 ,
4 x U.2 接口,
1 x M.2 Socket 3 插槽, 支持 M key, 2242/2260/2280/22110 类型存储设备 (SATA 与 PCIE 模式)
Expansion 3 x PCIe 3.0 x16 (x16 模式)
2 x PCIe 3.0 x16 (单槽 x16, 双槽x8/x8)
2 x PCIe 3.0 x16 (x8 模式)
Internal I/O 2 x USB 3.1 Gen 1 接口可扩展4 组外接式 USB 3.1 Gen 1 接口
1 x USB 2.0 接口可扩展2组外接式USB 2.0接口
1 x M.2 Socket 3 插槽,
1 x 串口连接插座(COM)
10 x SATA 6Gb/s设备连接插座
1 x TPM 接针
2 x 中央处理器风扇电源插槽 2 x 4 -pin
7 x 机箱风扇接口
1 x VROC_HW_Key
1 x 24-pin EATX主板电源插槽
1 x 前面板音频接口 (AAFP)
2 x 8-pin EATX 12 V 电源接口
1 x VGA connector(s)
1 x SMBus header(s)
1 x AUX panel 排针
1 x 6-pin EATX 12V_3 Power 接口
1 x 系统面板接口
4 x U.2 Connector (support U.2 NVMe device)
Backplane I/O 1 x PS/2 键鼠接口
2 x LAN (RJ45) 接口
4 x USB 3.1 Gen 1 接口
2 x USB 3.1 Gen 2 接口*4
4 x USB 2.0 接口
1 x 光纤S/PDIF数字音频输出接口
1 x USB BIOS Flashback™ 按钮
1 x 8声道音频接口
Features ProCool Power Connector
USB BIOS Flashback™
ASUS PIKE SAS upgrade kit*3
Dimensions EEB 版型结构
12 英寸 x 13 英寸 ( 30.5 厘米 x 33 厘米 )
Remarks * 双 Intel® 插槽 P/LGA 3647(方形)
*1 多显卡支持的实际数量因厂商的显卡而异。 请事先咨询厂商。
*2 由于 HDA 带宽限制,8 声道音效不支持 32 位/192kHz。 32 位/192kHz 仅在 Windows 10 下可用
*3 关于支持的附加卡,请查看 AVL 清单
*4 1 个 Type A,1 个 Type C
*5 5 个在前,2 个在后